Bochum [Germany], Midazolam increased the likelihood of adequate oxygen saturation and CO2 levels in the blood when the patient required anesthesia after successful resuscitation. There was no increased risk of subsequent drop in blood pressure or circulatory arrest "This special group of patients, who have been successfully resuscitated, should undoubtedly be included in pre-hospital anesthesia guidelines. De Gerrit Jansen, lead author of the study published in Deutsches Arzteblat International believes that midazolam has a particularly good effect in this group of patients. In the event of cardiac arrest, rapid intervention is essential: if first aiders take resuscitation measures at the right time, the patient's circulation can be restored. The scenario of the case can be restarted in the best way.“However, it is often the case that the patient has not yet regained consciousness,” At this stage, there are many factors that can affect the chances of subsequent survival due to circulatory disruption. Some patients exhibit protective reactions after resuscitation, such as coughing or defensive movements, which make the job of emergency responders more difficult. They often have to perform extended airway management, for example intubating the patient in the same way as during surgery. This requires frequent sedation or anesthesia,” Jensen explains. Until now, there has been concern that anesthetic drugs might have negative effects on the circulatory system, which has only just been restored.According to the study, however, this is not the case. Of the 571 people in the study who survived cardiac arrest and were hospitalized, 395 were sedated, 249 of them when given midazolam. The oxygen saturation level in his blood increased two-fold after the cardiac arrest. Administered. The likelihood of effectively expelling carbon dioxide increased by 1.6 times with the drug. "Our statistical methods confirmed the association between these results and the administration of midazolam without any indication of negative circulatory effects," says Gerrit Jensen. The European guidelines from the European Resuscitation Council do not yet set any specific recommendations for potential anesthetic drugs," Jansen explains.“Patients with heart failure are not mentioned in the German guidelines for pre-hospital anesthesia for patients at cardiovascular risk. We have therefore conducted pioneering research in this area, the results of which have been incorporated into recommendations for the benefit of patients. should be done."