Liverpool travel to east London after Wednesday's derby defeat to Everton dealt a huge blow to their title hopes, leaving them third in the table, two points behind Manchester City and three behind Arsenal, while City had a game in hand. Klopp's side were again lacking energy at Goodison Park, and with less than 72 hours to prepare, it is difficult to see how it can recover physically against a team that tests it from set pieces. Going to do – as Everton did.

The good news for Liverpool is that West Ham are also tired after reaching the Europa League quarter-finals, with the club surrounded by rumors that Julen Lopetegui is being replaced as coach by David Moyes at the end of the season.

The other two decisive games are on Sunday, with league leaders Arsenal traveling to north London to play traditional rivals Tottenham in a vital game for both sides.

Arsenal's impressive defeat of Chelsea on Wednesday means they have a one-point lead over Manchester City, but City have a game in hand.Mike Arteta's side will have to keep their cool against an opponent who also needs a win. Tottenham sit fifth in the table, six points behind Aston Villa, but have two games in hand if they want to stay in the race. If yes, then three numbers are important. Next season's Champions League. Spurs have not played a match since April 1 when they lost 4–0 to Newcastle, and at this stage of the season, it is difficult to know whether that break will allow tired legs to recover or their rhythm to recover. Will break.

Manchester City thrashed Brighton 4-0 on Thursday night with Phil Foden and Kevin De Bruyne in fine form as they visit struggling Nottingham Forest on Sunday. Forest's defeat to Everton last weekend left them one point above Luton Town and Luton can move two points above Nuno Espirit Santo's side if they win away to mid-table Wolverhampton on Saturday afternoon.If Luton lose on Saturday, it could take some of the pressure off Forest against Guardiola's side, who have Erling Haaland the only doubt over his fitness, but the way Manchester City demolished Brighton. Turns out they peaked at the right time.

Aston Villa will move nine points ahead of Tottenham if they beat disorganized Chelsea on Saturday. Unai Emery extended his contract with the club for another season in the week, while Chelsea suffered a 5–0 humiliation at the hands of Arsenal, needing to show some sort of response.

Chelsea have the power to hurt Villa on a good day, but Villa's duo of Ollie Watkins and Leon Bailly are far more effective in front of goal.

Elsewhere, Newcastle United must keep up the pressure for a top-six finish, which could confirm Sheffield United's return to the Championship on Saturday.Manchester United currently sit sixth but have been extremely irregular in recent games and Burnley should see the trip to Old Trafford as an opportunity to overtake Luton in their survival bid. Everton are almost safe after consecutive wins, while Brentford's five-match unbeaten run has also taken them closer to ensuring top-flight survival. Finally, Fulham and Crystal Palace, Bournemouth and Brighton play two mid-table derbies in which there is nothing at stake but glory.