Lupus is an autoimmune inflammatory disease known for its effects on multiple organs, including the brain.

These mental health and neurological symptoms, such as depression, hallucinations, and loss of balance, can act as an early warning sign that a person is approaching a “flare-up,” where their illness gets worse for a period. , said the team led by university researchers. Cambridge and King's College London in the UK.

For the study, they surveyed 676 people with lupus and 400 physicians, as well as conducted detailed interviews with 69 people with systemic autoimmune rheumatic diseases (including lupus) and 50 physicians.

The results, published in the journal eClinicalMedicine, showed that dream sleep disruption was the most common symptom, experienced by three out of five patients, with a third of whom developed lupus disease after a year.Only one in four patients reported hallucinations, seen in 85 percent of people with lupus.

Additionally, three out of five patients with lupus and one out of three with other rheumatology-related conditions also reported increasingly disrupted dreams during sleep.

, Patients reported that the nightmares were often very distressing, involving attacks, being trapped, being crushed, or falling.

Melanie Sloan of the University of Cambridge called on doctors to talk to patients about these types of symptoms and document each patient's progress.

“Patients often know which symptoms are a bad sign that their disease is about to progress, but both patients and doctors may be reluctant to discuss mental health and neurological symptoms, especially if they don't realize that these are autoimmune. may be part of the disease,” said lead author Melanie, from the university's department of public health and primary care.