The studies, led by researchers at the Dana-Farber Cancer Institute in the United States, have encouraging implications for breast cancer patients.
Two studies focused on breastfeeding after breast cancer diagnosis and treatment.
They found that it was safe and feasible to breastfeed young patients carrying specific genetic variations without increasing the risk of cancer recurrence or cancer in the other breast, and that it was safe and feasible to breastfeed patients who were hormone receptor positive (HR+). ) breast cancer who conceived after a temporary interruption of endocrine therapy.
The third study demonstrated that a telephone training program can significantly increase physical activity in overweight patients, potentially improving their outcomes.
The studies were presented at the "European Society for Medical Oncology (ESMO) Congress 2024" in Barcelona, Spain.
The first study was a collaboration between researchers from 78 hospitals and cancer treatment centers around the world. The study involved 474 patients with inherited mutations in the BRCA1 or BRCA2 cancer susceptibility genes who became pregnant after being diagnosed with stage I-III invasive breast cancer at age 40 or younger.
The second study provides breastfeeding results from the POSITIVE trial that demonstrated the early safety of temporarily stopping endocrine therapy to attempt pregnancy. A key secondary endpoint was breastfeeding outcomes.
The study included 518 patients aged 42 years or younger with stage I-III HR+ breast cancer.
Of these patients, 317 had a live birth and 196 chose to breastfeed. Breast-conserving surgery was a key factor that favored breastfeeding.
"These studies provide the first evidence on the safety of breastfeeding after breast cancer both in young patients who carry BRCA variations that predispose to breast cancer, and in patients who conceived after stopping endocrine therapy," Ann said. Partridge, founder and director of the program. for young adults with breast cancer at Dana-Farber.
The findings emphasize the possibility of meeting maternal and infant needs without compromising maternal security.
The third study was based on data from the Breast Cancer Weight Loss (BWEL) trial, which explores whether participating in a weight loss program after a breast cancer diagnosis can reduce the risk of cancer recurrence in women with an index of body mass (BMI) range of overweight or obesity.
"Our results show that a telephone intervention for weight loss can motivate this group of patients to be more physically active," said the study's first author, Jennifer Ligibel.
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Two studies focused on breastfeeding after breast cancer diagnosis and treatment.
They found that it was safe and feasible to breastfeed young patients carrying specific genetic variations without increasing the risk of cancer recurrence or cancer in the other breast, and that it was safe and feasible to breastfeed patients who were hormone receptor positive (HR+). ) breast cancer who conceived after a temporary interruption of endocrine therapy.
The third study demonstrated that a telephone training program can significantly increase physical activity in overweight patients, potentially improving their outcomes.
The studies were presented at the "European Society for Medical Oncology (ESMO) Congress 2024" in Barcelona, Spain.
The first study was a collaboration between researchers from 78 hospitals and cancer treatment centers around the world. The study involved 474 patients with inherited mutations in the BRCA1 or BRCA2 cancer susceptibility genes who became pregnant after being diagnosed with stage I-III invasive breast cancer at age 40 or younger.
The second study provides breastfeeding results from the POSITIVE trial that demonstrated the early safety of temporarily stopping endocrine therapy to attempt pregnancy. A key secondary endpoint was breastfeeding outcomes.
The study included 518 patients aged 42 years or younger with stage I-III HR+ breast cancer.
Of these patients, 317 had a live birth and 196 chose to breastfeed. Breast-conserving surgery was a key factor that favored breastfeeding.
"These studies provide the first evidence on the safety of breastfeeding after breast cancer both in young patients who carry BRCA variations that predispose to breast cancer, and in patients who conceived after stopping endocrine therapy," Ann said. Partridge, founder and director of the program. for young adults with breast cancer at Dana-Farber.
The findings emphasize the possibility of meeting maternal and infant needs without compromising maternal security.
The third study was based on data from the Breast Cancer Weight Loss (BWEL) trial, which explores whether participating in a weight loss program after a breast cancer diagnosis can reduce the risk of cancer recurrence in women with an index of body mass (BMI) range of overweight or obesity.
"Our results show that a telephone intervention for weight loss can motivate this group of patients to be more physically active," said the study's first author, Jennifer Ligibel.
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