Djokovic's withdrawal means Casper Ruud has advanced to the semi-finals and will play either Germany's Alexander Zverev or Australia's Alex de Minaur in the last four on Friday.

The Serbian world No. 1 said after his five-set win over Francisco Cerundolo on Monday that he was managing the problem for Paris, and the injury became more serious during the fourth-round win over Argentina. "I don't know what will happen tomorrow or the day after if I'll be able to get on the court and play," Djokovic said Monday night. "You know, I hope so." Let's see what happens."

With Djokovic, who was hoping to win a record-extending 25th Grand Slam title, withdraw from the French Open, a new men's singles champion will be crowned in Paris on Sunday.

When the next rankings are published the day after the end of Roland-Garros, Sinner will make history as the new world No. 1 for Italy.

Current world No. 1 Djokovic had to reach at least the French Open final to have a chance of dethroning Sinner from the top spot. But his withdrawal from the tournament on Tuesday means the Italian will take over from the Serb at the top of the men's rankings.

Sinner would become the first Italian men's singles world No. 1. He is back to play on Friday

On Tuesday, Sinner defeated 10th seed Grigor Dimitrov in straight sets 6-2, 6-4, 7-6(3) and will next face Carlos Alcaraz or Stefanos Tsitsipas on Friday.

In the top half of the draw, one of Casper Ruud, Alexander Zverev, or Alex de Minaur will be a finalist on Sunday.

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