The roles eventually went to actors Bob Saget, Dave Coulier, and John Stamos, respectively.

"I auditioned for all three parts of 'Full House,'" Duchovny said on his podcast 'Fail Better.'

“First of all, I think, he chose me for the father's role. Then they chose me to play Stamos. And then they got me for another guy. I was thinking, 'I have to get one of these, and it will change my life.'"

Duchovny said he had a lot of pilots in mind when he first came to Los Angeles, and he thought every single one of them would get a break, reports Deadline.com.

“I just had to be able to pay my rent, too.”

The actor finally got his big break in 'The X-Files', where he played FBI Special Agent Fox Mulder.

Duchovny also said that at the time he auditioned for 'Full House', the sitcom genre was not a good fit for him.

“I was really bad at that kind of thing,” he said.

“I didn't know how to do this sitcom. I don't know what they were thinking, that they thought I would exist in that world. I mean, I guess I could learn, but I wasn't ready for the kind of energetic performance they required.

Duchovny later starred in the drama series 'Californication' in 2007 and most recently starred opposite Meg Ryan in the 2023 romantic comedy 'What Happens Later'.