It comes after reports that AstraZeneca admitted for the first time in court documents that its vaccine, developed in partnership with Oxford University, could increase the risk of rare and serious blood clots.
The Oxford-AstraZeneca Covid vaccine, sold as Covishield in India and Vaxzevri in Europe, is a viral vector vaccine developed using a modified chimpanzee adenovirus ChAdOx1.
Covishield is manufactured and marketed in India in partnership with Seru Institute of India
, was administered widely in the country
9 percent of the Indian population.
“Thrombotic thrombocytopenic syndrome (TTS) is one of the rare but very serious adverse effects that have occurred as part of vaccine-induced immune thrombocytopenic purpura (VITTP). Infectious disease expert Dr Ishwar Gilada told IANS that the incidence is as low as one in 50,00 (0.002 per cent), but in a larger population, this number becomes much larger.Co-Chair Dr. Rajeev Jayadevan said, “TTS is a very rare condition resulting from an abnormal immune response, although it has many causes, it has also been linked to Adenovirus Vecto vaccines and WHO approved its use on May 27, 2021 Has published a report about." The National Covid-19 Task Force of the Indian Medical Association told IANS.
What is the matter? The British-Swedish multinational pharmaceutical company has admitted for the first time in UK court documents that its Covid vaccine may pose a risk of rare blood clots, the Telegraph reports.
As many as 51 cases have been filed in the UK High Court against the pharmaceutical giant over claims that its Covid vaccine caused death and serious injury.
The report said victims and grieving relatives are demanding compensation, which has been estimated at £100 million.Although AstraZeneca is contesting those claims, "it admitted in a legal document submitted to the High Court in February that its Covid vaccine 'can, in very rare cases, cause TTS'", the report said .
TTS causes blood clots to form in people and the platelet count in the blood decreases.
Link to AstraZeneca's Covid vaccine and TTS? In India, about 90 percent of people who received the Covid vaccine received the AstraZeneca vaccine, known as Covishield in India. It is made from a harmless cold virus that comes from chimpanzees and is called adenovirus.
“Once this virus is genetically modified or engineered so that it matches SARS-CoV-2 which causes COVID-19, it works on the spike protein.Therefore, th vaccine has been incorporated with the S spike protein genetic sequence,” said Dr Ishwar, Secretary General People's Health Organisation-India, Mumbai.
Explaining the mechanism of possible TTS risk, he said that the vaccine I injected into the arm is in the deltoid muscle. However, “sometimes instead of just entering the muscles, it also enters the bloodstream. Once it enters the bloodstream, the adenovirus present in the vaccines acts like a magnet, having a special attraction towards a type of protein in the blood called platelet factor 4 (PF4),'' said the doctor. .
“Although PF4 is normally used by the body to promote blood coagulation, in rare cases, the body's immune system confuses it as a foreign body or foreign invader and then attacks it. Releases antibodies for.,
"It is theorized that such antibodies react and combine with PF4 to form the blood clots that have been most commonly associated with the vaccine. Such clots in the brain and heart can cause devastating adverse effects," the doctor said.
Should everyone taking the Covishield vaccine be worried?
“No, we don't need it because this has happened to very few people,” said Dr. Eshwar.
“The difficulty is to distinguish between complications that are caused by Covid itself or long-Covid or the vaccine. This remains a matter of debate and indistinguishability for the scientific community as well as the legal fraternity.,
Importantly, Dr Rajeev said, “people who have been vaccinated have a lower risk of death from Covid as well as complications such as post-Covid seizures and subsequent stroke.”
“Although vaccines have extremely rare serious side effects, the benefits outweigh the risks. Covid vaccines have prevented hundreds of thousands of people from dying. For example, in the US, 232,000-318,000 people have died from Covid, due to refusal to get vaccinated due to disproportionate fear of vaccination,” he said.
The Oxford-AstraZeneca Covid vaccine, sold as Covishield in India and Vaxzevri in Europe, is a viral vector vaccine developed using a modified chimpanzee adenovirus ChAdOx1.
Covishield is manufactured and marketed in India in partnership with Seru Institute of India
, was administered widely in the country
9 percent of the Indian population.
“Thrombotic thrombocytopenic syndrome (TTS) is one of the rare but very serious adverse effects that have occurred as part of vaccine-induced immune thrombocytopenic purpura (VITTP). Infectious disease expert Dr Ishwar Gilada told IANS that the incidence is as low as one in 50,00 (0.002 per cent), but in a larger population, this number becomes much larger.Co-Chair Dr. Rajeev Jayadevan said, “TTS is a very rare condition resulting from an abnormal immune response, although it has many causes, it has also been linked to Adenovirus Vecto vaccines and WHO approved its use on May 27, 2021 Has published a report about." The National Covid-19 Task Force of the Indian Medical Association told IANS.
What is the matter? The British-Swedish multinational pharmaceutical company has admitted for the first time in UK court documents that its Covid vaccine may pose a risk of rare blood clots, the Telegraph reports.
As many as 51 cases have been filed in the UK High Court against the pharmaceutical giant over claims that its Covid vaccine caused death and serious injury.
The report said victims and grieving relatives are demanding compensation, which has been estimated at £100 million.Although AstraZeneca is contesting those claims, "it admitted in a legal document submitted to the High Court in February that its Covid vaccine 'can, in very rare cases, cause TTS'", the report said .
TTS causes blood clots to form in people and the platelet count in the blood decreases.
Link to AstraZeneca's Covid vaccine and TTS? In India, about 90 percent of people who received the Covid vaccine received the AstraZeneca vaccine, known as Covishield in India. It is made from a harmless cold virus that comes from chimpanzees and is called adenovirus.
“Once this virus is genetically modified or engineered so that it matches SARS-CoV-2 which causes COVID-19, it works on the spike protein.Therefore, th vaccine has been incorporated with the S spike protein genetic sequence,” said Dr Ishwar, Secretary General People's Health Organisation-India, Mumbai.
Explaining the mechanism of possible TTS risk, he said that the vaccine I injected into the arm is in the deltoid muscle. However, “sometimes instead of just entering the muscles, it also enters the bloodstream. Once it enters the bloodstream, the adenovirus present in the vaccines acts like a magnet, having a special attraction towards a type of protein in the blood called platelet factor 4 (PF4),'' said the doctor. .
“Although PF4 is normally used by the body to promote blood coagulation, in rare cases, the body's immune system confuses it as a foreign body or foreign invader and then attacks it. Releases antibodies for.,
"It is theorized that such antibodies react and combine with PF4 to form the blood clots that have been most commonly associated with the vaccine. Such clots in the brain and heart can cause devastating adverse effects," the doctor said.
Should everyone taking the Covishield vaccine be worried?
“No, we don't need it because this has happened to very few people,” said Dr. Eshwar.
“The difficulty is to distinguish between complications that are caused by Covid itself or long-Covid or the vaccine. This remains a matter of debate and indistinguishability for the scientific community as well as the legal fraternity.,
Importantly, Dr Rajeev said, “people who have been vaccinated have a lower risk of death from Covid as well as complications such as post-Covid seizures and subsequent stroke.”
“Although vaccines have extremely rare serious side effects, the benefits outweigh the risks. Covid vaccines have prevented hundreds of thousands of people from dying. For example, in the US, 232,000-318,000 people have died from Covid, due to refusal to get vaccinated due to disproportionate fear of vaccination,” he said.
